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关键词： 计算机辅助设计   计算机辅助制造   树脂高嵌体   咬合重建   牙齿重度磨耗  

摘要： 目的:分析计算机辅助设计/辅助制造(CAD/CAM)树脂高嵌体咬合重建对牙齿重度磨耗老年患者咀嚼功能的影响。方法:选取我院2020年12月-2023年12月收治的60例牙齿重度磨耗老年患者作为观察对象,采用数字表随机法分为观察组和对照组,各30例。对照组通过常规疗法进行咬合重建,观察组通过CAD/CAM树脂高嵌体进行咬合重建,对比两组咬合重建效果以及对患者咀嚼功能的影响。结果:治疗90d后,观察组咀嚼效率高于对照组,CMI评分低于对照组(P<0.05);观察组咬合重建优良率高于对照组(P<0.05);观察组单牙平均制备时间、平均调[牙合]时间均短于对照组(P<0.05);观察组满意度各维度评分均高于对照组(P<0.05)。结论:CAD/CAM树脂高嵌体咬合重建在牙齿重度磨耗老年患者中具有良好的效果,成功率较高,能够有效提高患者的咀嚼效率,缓解颞下颌关节功能障碍,同时患者对治疗各个方面的满意度较高,接受能力强,值得在临床推广应用。

关键词： 结构性黏土   结构性剑桥模型   有效应力路径   亚屈服   附加孔隙比  

摘要： 室内外试验和工程实践都表明天然沉积黏土具有一定的结构性,因此建立结构性本构模型对准确预测天然黏土的力学响应和解决实际岩土工程问题具有重要意义。首先,基于结构性黏土的三轴固结不排水试验的有效应力路径对结构性剑桥(SCC)模型进行了两点改进:(1)对附加孔隙比Δe的计算公式进行了修正,可以准确模拟结构性黏土超过临界状态线后的有效应力路径;(2)考虑了屈服面内的塑性即亚屈服特性,可以较好地模拟屈服面内的有效应力路径然后,利用修正结构性剑桥(MSCC)模型对结构性黏土的侧限压缩试验、三轴固结不排水和三轴固结排水试验进行了模拟计算,并与试验结果和SCC模型的计算结果进行了对比分析,结果表明MSCC模型可以更好地模拟结构性黏土的三轴不排水有效应力路径以及侧限压缩和三轴固结排水试验的应力应变曲线。最后,对MSCC模型中的参数β(屈服面内塑性变形参数)、p'_(yi)(初始结构屈服应力)、Δe_(i)(初始附加孔隙比)、b(结构破损速率)、γ(剪切引起结构破损的参数)和ω(反映结构性对塑性流动准则的影响)进行了参数敏感性分析,结果表明参数β影响结构性黏土屈服面内的有效应力路径,参数p'_(yi)影响峰值强度,参数Δe_(i)影响残余强度,参数b和γ影响峰值后的强度衰减速率,参数ω影响强度开始衰减时的偏应变大小。

关键词： Autocorrelation   Control Loop Performance Assessment   Offshore Oil Production   Process monitoring   Slugging Flow  

摘要： Severe slugging is a prevalent issue in offshore oil wells that significantly hampers oil production. While active pressure control has proven effective in mitigating this problem, determining optimal setpoints remains a manual and labor-intensive procedure. This study introduces the Input-Output Cross Autocorrelation Diagram (IO-CAD), which examines both input and output autocorrelations to provide a more comprehensive assessment of control loops compared to previous methods that only use output autocorrelation data. Four indicators based on IO-CAD were developed and tested in two case studies involving offshore oil production. They were compared to an oscillation detection method published in the literature, as oscillations in the control loop may indicate the slugging flow. Early detection of slugging patterns is crucial in offshore oil production to prevent severe slugging and stabilize control loops. The results demonstrated that the IO-CAD indicators are robust against setpoint changes, disturbances, and noise in the control loop performance assessment, while the oscillation detection method from the literature is sensitive to measurement and process noise, as well as control loop oscillations.

关键词： cardiovascular   diabetes   hypertension   nature   walkability   ADI   area deprivation index   ASCVD   atherosclerotic cardiovascular disease   BMI   body mass index   CAD   coronary artery disease   CV   NDVI   normalized difference vegetation index   PAD   peripheral artery disease   RRR   relative risk ratio  

摘要： Green space has been linked with cardiovascular (CV) health. Nature access and quality may have significant impact on CV risk factors and health.

摘要： Introduction: Coronary artery calcification (CAC) is a hallmark of atherosclerotic cardiovascular disease. Several clinical risk scores have been developed to predict the likelihood of CAC including the ‘full’ MESA (Multi-Ethnic Study of Atheroscl...

关键词： CAD   coronary artery disease   EMA   European Medicines Agency   HDL   high-density lipoprotein   IBD   inflammatory bowel diseases   JAKi   Janus kinase inhibitors   NHIS   National Health Interview Survey  

摘要： Janus kinase inhibitors (JAKi), particularly upadacitinib, are among the most efficacious therapies for patients with inflammatory bowel diseases (IBDs), particularly ulcerative colitis. However, in 2019, regulatory agencies modified the label for...

关键词： 锂电池   钢铁   市场监督管理总局   纺织品  

摘要： 为推动产品碳足迹管理体系建设,加快建立产品碳标识认证制度,近日,国家市场监督管理总局等四部委联合公布产品碳足迹标识认证试点名单。据介绍,此次试点对象将优先聚焦市场需求迫切、外贸压力严峻、减排贡献突出、数据收集完整、产业链供应链带动明显的锂电池、光伏产品、钢铁、纺织品、电子电器、轮胎、水泥、电解铝、尿素、磷铵、木制品等产品。其中,水泥产品碳足迹标识认证将在宁夏银川开展试点。

关键词： Industry 5.0 (I5.0)   Human-Machine Collaboration   Computer-Aided Design (CAD)   Cognitive Load Reduction(CWA)   Optical Character Recognition (OCR)  

摘要： In the realm of manufacturing, Efficient cost estimation from customer data, like CAD drawings, is essential for optimizing resource allocation and maintaining a competitive advantage. These efforts align with I5.0 principles to enable a hybrid-intelligence-based approach for extracting the data. This selective interaction enhances human-machine collaboration and enables operators of various skill levels to participate in the process. The solution aims to streamline data extraction, minimize errors, and improve operator efficiency while maintaining operator control. In the use case of a Small-to-Medium Equipment Manufacturer specializing in the production of machine and plant parts, significant challenges arose from their manual, time-intensive process. For example, extracting dimensions from Computer-Aided Design (CAD) drawings involved manually entering data into spreadsheets for material cost estimation. This process required substantial cognitive effort and was prone to human error. To address this, this paper proposes a user-centric software design leveraging Optical Character Recognition (OCR) to detect and display dimensions from CAD drawings.

关键词： Ischemic cardiomyopathy   Revascularization   Percutaneous coronary intervention   Chronic total occlusion   Complex high-risk indicated patients   CAD   coronary artery disease   PCI   percutaneous coronary intervention   MI   myocardial infarction   CHIP   complex high risk indicated patients   CTO   chronic total occlusion   CVD   cardiovascular disease   HF   heart failure   ICM   ischemic cardiomyopathy   LV   left ventricular   LVEF   left ventricular ejction fraction   GDMT   guideline directed medical therapy   ACS   acute coronary syndrome   RCTs   randomized controlled trials   CABG   coronary artery bypass graft   NYHA   New York Heart Association   ACEI   angiotensin converting enzyme inhibitor   ARB   angiotensin receptor blocker   ARNI   angiotensin receptor neprilysin inhibitor   MRA   mineralocorticoid receptor antagonist   QoL   quality of life   PET   Positron Emission Tomography   SPECT   single-photon emission computed tomography   DSE   dobutamine stress echocardiography (DSE)   TVD   three vessel disease   CCS   Canadian Cardiology Society   KCQ   Kansas City Cardiomyopathy Questionnaire   EQ-5D-5L   EuroQol Group 5-Dimensions 5-Level Questionnaire   SCD   sudden cardiac death   ICD   implantable cardioverter-defibrillators   MACE   major adverse cardiovascular events   NSTEMI   non-ST elevation myocardial infarction   LAD   left anterior descending   OM1   first marginal branch   LCX   left circumflex   RCA   right coronary artery   RPL   right posterior lateral   SS-I   Syntax Score I   SS-II   Syntax Score II  

摘要： Ischemic cardiomyopathy (ICM) is characterized by myocardial dysfunction due to myocardial ischemia, associated with the presence of significant coronary artery disease (CAD). We provide a comprehensive review of the current evidence for coronary revascularization in ICM, including consideration of the different modalities of coronary artery bypass grafting and percutaneous coronary intervention. In addition to a contemporary assessment of the literature, we aim to provide real-world insights and perspectives to guide clinical decision-making in this heterogeneous and complex patient population.

关键词： 四灵   空间效果   纺织品设计   设计主题   设计说明   层次感   神兽   展翅翱翔  

摘要： 设计说明:“四灵瑞纹”系列作品以中国传统四大神兽青龙、白虎、朱雀和玄武为设计主题,通过浓厚的东方色彩与细腻的线条,塑造出四灵各自独特的形象与气韵,呈现其守护四方的神圣性和祥瑞意涵。设计中,青龙蜿蜒腾空象征生机,白虎威猛雄健象征正义,朱雀展翅翱翔体现祥瑞天降,玄武则以龟蛇共生表现北方的稳重与长久。每一神兽的形象都巧妙地融入云纹、山川、花卉等传统元素,寓意天地和谐与四方守护,营造出吉祥安定的整体意境。分层手法的运用进一步增强了作品的层次感与空间效果,使四灵图案更具立体感,彰显出庄重与独特的美学韵味。