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关键词： aortic stenosis   CAD   TAVR  

摘要： Corresponding Author

关键词： coronary artery bypass grafting   percutaneous coronary intervention   surgical aortic valve replacement   transcatheter aortic valve replacement   AR   aortic regurgitation   AS   aortic stenosis   AVA   aortic valve area   CABG   coronary artery bypass graft   CAD   coronary artery disease   FFR   fractional flow reserve   PCI   percutaneous coronary intervention   RCT   randomized controlled trial   SAVR   surgical aortic valve replacement   STS   Society of Thoracic Surgeons   TAVR   transcatheter aortic valve replacement  

摘要： Severe aortic stenosis (AS) coexists with coronary artery disease (CAD) in approximately 50% of patients. The preferred treatment is combined surgical aortic valve replacement (SAVR) and coronary artery bypass grafting (CABG). However, transcatheter aortic valve replacement (TAVR) along with percutaneous coronary intervention (PCI) has emerged as a viable alternative.

关键词： CAD   HILIC   Polyethylenimine   Stilbene   Vitis vinifera  

摘要： The characterization of plant extracts is usually accomplished by reverse-phase liquid chromatography, but the development of new complementary approaches, such as HILIC, offers an orthogonal method. In this study, five HILIC stationary phases were evaluated to assess their ability to retain polyphenols. They were selected to cover the main different HILIC mechanisms: bare silica; silica with ethylene bridge; neutral amide; amino; zwitterionic. A total of 31 polyphenol standards were used for the screening, including 9 stilbenes, 8 flavonoids, 6 anthocyanins, and 8 phenolic acids. Three different detections were tested: diode array detector, charged aerosol detector and mass spectrometry.