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关键词： 船用发动机   凸轮-滚轮-滚轮销   重载工况   混合热弹流润滑  

摘要： 凸轮-滚轮-滚轮销是大功率船用发动机燃油喷射装置的核心部件,工作期间承受来自喷油器的瞬时燃油压力,工作条件极为苛刻,极易发生滚轮打滑和磨损失效现象。为了分析该摩擦副的性能,建立了船用发动机重载工况下凸轮-滚轮-滚轮销相互耦合的混合热弹流润滑模型,获得了该摩擦副在一个工作循环(即凸轮旋转一周,360°转角)的摩擦学结果。分析表明,来自喷油器的燃油压力会显著降低凸轮-滚轮-滚轮销摩擦副之间的油膜厚度,同时产生较为严重的微凸体接触,并且凸轮-滚轮-滚轮销之间的耦合效应是造成滚轮打滑的主要原因。凸轮-滚轮从动件单元中的摩擦损失以滚轮-滚轮销副为主,其在工作过程中会产生显著的摩擦温升。基于该模型,还研究了滚轮销修型对减摩和降磨的影响,发现型线改进后可以降低约7.2%的摩擦损失以及12.8%的磨损负载。此外,实验与仿真结果的对比表明模型是有效的并且预测结果也是合理的。

关键词： Dental materials   Prosthetic dentistry   Fracture mechanics   Hybrid ceramics   Adhesion   Cementation   Implant prostheses  

摘要： AbstractObjectivesTo compare the interfacial fracture toughness (IFT) with or without aging, of four different classes of CAD-CAM ceramic and composite materials bonded with self-adhesive resin cement to titanium alloy characteristic of implant abutments. MethodsHigh translucent zirconia (Katana; KAT), lithium disilicate-based glass-ceramic (IPS. ***; EMX), polymer-infiltrated ceramic network material (PICN) (Vita Enamic; ENA), and dispersed filler composite (Cerasmart 270; CER) were cut into equilateral triangular prisms and bonded to titanium prisms with identical dimensions using Panavia SA Cement Universal. The surfaces were pretreated following the manufacturers’ recommendations and developed interfacial area ratio (Sdr) of the pretreated surfaces was measured. IFT was determined using the Notchless Triangular Prism test in a water bath at 36 °C before and after thermocycling (10,000 cycles) (n = 40 samples/material). ResultsIFT of the materials ranged from 0.80 ± 0.25 to 1.10 ± 0.21 MPa.m 1/2 before thermocycling and from 0.71 ± 0.24 to 1.02 ± 0.25 MPa.m 1/2 after thermocycling. There was a statistical difference between IFT of CER and the two top performers in each scenario: KAT and EMX before aging, and KAT and ENA after aging. Thermocycling significantly decreased IFT of EMX. The Weibull modulus of IFT was similar for all materials and remained so after thermocycling. Sdr measurements revealed that ENA (7.60)>Ti (4.97)>CER (2.85)>KAT (1.09)=EMX (0.96). SignificanceDispersed filler CAD-CAM composite showed lower performance than the other materials. Aging only affected IFT of Li-Si glass-ceramic, whereas zirconia and PICN performed equally well, probably due to their chemical bonding potential and surface roughness respectively.

关键词： biomarkers   cardio-oncology   cardiotoxicity   cardiovascular imaging   disease prevention   risk assessment   ACHD   adult congenital heart disease   ADT   androgen deprivation therapy   AF   atrial fibrillation   AIC   anthracycline-induced cardiotoxicity   BP   blood pressure   BRAF   rapidly accelerated fibrosarcoma B type   BTKi   Bruton tyrosine kinase inhibitor   CAC   coronary artery calcium   CAD   coronary artery disease   CAR-T   chimeric antigen receptor T cell   CIED   cardiac implantable electronic device   CLL   chronic lymphocytic leukemia   CMR   cardiac magnetic resonance   CRS   cytokine release syndrome   CT   computed tomography   cTn   cardiac troponin   cTnI   cardiac troponin I   CTRCD   cancer therapy–related cardiovascular dysfunction   ECG   electrocardiogram   ESC   European Society of Cardiology   GLS   global longitudinal strain   GnRH   gonadotrophin-releasing hormone   HbA1c   glycated hemoglobin   HSCT   hematopoietic stem cell transplantation   HER2   human epidermal growth factor receptor 2   HFA-ICOS   Heart Failure Association–International Cardio-Oncology Society   ICI   immune checkpoint inhibitor   IHD   ischemic heart disease   IMID   immunomodulatory agent   LV   left ventricular   LVEF   left ventricular ejection fraction   MEK   mitogen-activated extracellular signal-regulated kinase   MM   multiple myeloma   NT-proBNP   N-terminal pro–B-type natriuretic peptide   PI   proteasome inhibitor   RCT   randomized controlled trial   TKI   tyrosine kinase inhibitor   TTE   transthoracic echocardiography   VEGFi   vascular endothelial growth factor inhibitor  

摘要： Baseline cardiovascular assessment before the initiation of potentially cardiotoxic cancer therapies is a key component of cardio-oncology, aiming to reduce cardiovascular complications and morbidity in patients and survivors. Recent clinical practice guidelines provide both general and cancer therapy–specific recommendations for baseline cardiovascular toxicity risk assessment and management, including the use of dedicated risk scores, cardiovascular imaging, and biomarker testing. However, the value of such interventions in altering disease trajectories has not been established, with many recommendations based on expert opinion or Level of Evidence: C, studies with a potential for high risk of bias. Advances in understanding underlying mechanisms of cardiotoxicity and the increased availability of genetic and immunologic profiling present new opportunities for personalized risk assessment. This paper evaluates the existing evidence on cardiovascular care of cancer patients before cardiotoxic cancer therapy and highlights gaps in evidence and priorities for future research.

关键词： 智能可穿戴   柔性电子材料   传感器  

摘要： 智能可穿戴纺织品作为纺织材料与信息技术高度融合的产物,近年来在健康监测、运动健身、医疗、军事、娱乐及时尚等领域展现出巨大的应用潜力。本文综述了智能可穿戴纺织品的市场现状、技术挑战、研发策略及未来发展趋势,重点探讨了材料科学、传感器技术、数据处理能力等方面的互联互通,并提出了相应的解决方案和布局规划。

关键词： 再生资源行业   废旧纺织品   循环利用   流通秩序   产学研用   科研成果   再生资源回收利用   优质资源  

摘要： 10月17日至19日,由中国再生资源回收利用协会(以下简称中再生协会)主办的“2024废旧纺织品循环利用行业发展大会”在广州召开。会议由中再生协会废纺专业委员会、广州市格瑞哲再生资源股份有限公司、广州再生资源行业协会承办,南京再生资源行业协会、山东省再生资源协会、贵州省再生资源行业协会连联合协办。本届会议以“标准构建大体系,技术织就大市场”为主题,深入探讨生活源端废旧纺织品回收体系建设、国际国内二手服装流通秩序、废旧纺织品高值化利用路径等相关问题。主要聚焦消费后废旧纺织品循环利用的最新科研成果交流、先进技术的应用推广、产业政策解读以及优秀案例分享等内容,旨在汇聚产学研用的优质资源,构建一个高效、开放、共享的业内信息交流与合作平台。

关键词： anthracycline   biomarkers   cancer survivorship   diagnosis   heart failure   ACEI   angiotensin-converting enzyme inhibitor   BC   breast cancer   CAD   coronary artery disease   CCT   cardiac computed tomography   CMR   cardiac magnetic resonance   CTRCD   cancer therapy–related cardiac dysfunction   DD   diastolic dysfunction   eBC   early breast cancer   ESC   European Society of Cardiology   GLS   global longitudinal strain   HER2   human epidermal growth factor receptor 2   HF   HL   Hodgkin lymphoma   IC-OS   International Cardio-Oncology Society   LV   left ventricular   LVEF   left ventricular ejection fraction   nHL   non-Hodgkin lymphoma   NP   natriuretic peptide   NT-proBNP   N-terminal pro–B-type natriuretic peptide   OS   overall survival   ROS   reactive oxygen species   RT   radiotherapy   SNP   single-nucleotide polymorphism   TC   docetaxel and cyclophosphamide   TNBC   triple-negative breast cancer  

摘要： Since their introduction in the 1960s, anthracyclines have been a significant breakthrough in oncology, introducing dramatic changes in the treatment of solid and hematologic malignancies. Although new-generation targeted drugs and cellular therapies are revolutionizing contemporary oncology, anthracyclines remain the cornerstone of treatment for lymphomas, acute leukemias, and soft tissue sarcomas. However, their clinical application is limited by a dose-dependent cardiotoxicity that can reduce cardiac performance and eventually lead to overt heart failure. The field of cardio-oncology has emerged to safeguard the cardiovascular health of cancer patients receiving these therapies. It focuses on controlling risk factors, implementing preventive strategies, ensuring appropriate surveillance, and managing complications. This state-of-the-art review summarizes the current indications for anthracyclines in modern oncology, explores recent evidence on pathophysiology and epidemiology, and discusses advances in cardioprotection measures in the anthracycline-treated patient. Additionally, it highlights key clinical challenges and research gaps in this area.

摘要： Standard angled abutments could not provide an entryway sometime. In this case, implant angles were tilt and personal abutments are a solution for the clinician.

关键词： 新工科   化工制图与Auto CAD   教学改革  

摘要： 化工制图与Auto CAD化学工程与工艺专业的一门核心课程,具有较强的理论性和实践性,通过讲授工程制图的基本知识、化工设备图样、化工工艺图样,让学生掌握识图、阅图及绘图的基本能力,课程的教学质量将会直接影响到后续专业课学习、毕业设计质量及化工设计大赛的完成情况等。笔者结合多年的教学积累和教学反思,介绍了化工制图与Auto CAD在教学过程中存在的一些问题,阐述在教学中过程性改革的具体措施。通过改进教学模式,优化过程性评价,培养学生独立思考能力和动手实践能力,为化工企业输送应用型人才。

关键词： surface reconstruction   feature-preserving   discrete optimal transportation  

摘要： Feature-preserving mesh reconstruction from point clouds is *** methods tend to fit smooth surfaces and cannot be used to reconstruct sharp *** reconstruction methods are sensitive to noise and only interpolate sharp features when points are distributed on feature *** propose a watertight surface reconstruction method based on optimal transport that can accurately reconstruct sharp features often present in CAD *** formalize the surface reconstruction problem by minimizing the optimal transport cost between the point cloud and the reconstructed *** algorithm consists of initialization and refinement *** the initialization step,the convex hull of the point cloud is deformed under the guidance of a transport plan to obtain an initial approximate ***,the mesh surface was optimized using operations including vertex relocation and edge collapses/fips to obtain feature-preserving *** demonstrate that our method can preserve sharp features while being robust to noise and missing data.

关键词： 数码喷墨印花   数码印花   纺织品   时代特质   印染行业   绿色化   高端化   融合化  

摘要： 当前,数字技术在印染行业已得到广泛应用,数码喷墨印花作为具有全新时代特质与文化内涵的现代化生产力,顺应了高端化、数字化、绿色化、融合化发展新趋势,已成为产业新质发展的重要力量。为进一步推动数码喷墨印花行业提质增效、向新发展,加快形成具有高效能、高技术和高质量特征的新质生产力,10月26日,以“向新提质数创未来”为主题的2024全球纺织品数码喷墨印花柯桥峰会在柯桥举行。