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摘要： Ectodermal dysplasia (ED) affects oral structures, often necessitating prosthodontic interventions. Digital advancements like CAD/CAM enable the fabrication of RPDs, with PEEK emerging as a promising alternative to metal frameworks, addressing aesthetic and functional concerns associated with traditional approaches.

关键词： 变刚度关节   渐开线轮廓凸轮   杠杆原理   偏角解耦  

摘要： 针对当前的杠杆式变刚度关节存在的刚度与偏角耦合的缺点,提出一种变刚度关节设计方案。首先,提出了可调支点杠杆机构的结构方案。通过静力学模型分析得出关节刚度与偏角无关。进而,设计了调整杠杆机构支点位置的渐开线凸轮机构,使得凸轮转角与支点位置成线性关系,降低了关节刚度调节的难度。最后,设计并制作了变刚度关节的原理样机,分别进行了样机关节刚度特性以及刚度与偏角关系的仿真与实验,验证了变刚度原理的可行性以及刚度与偏角的解耦性。

关键词： GB/T 17592   禁用偶氮染料   纺织品   新、旧标准   差异  

摘要： GB/T 17592—2024《纺织品禁用偶氮染料的测定》于2024年3月15日发布,2025年4月1日开始实施。本文对纺织品禁用偶氮染料的测定新、旧标准进行详细的分析比较,加深对新方法的理解,为日常快速正确地运用新方法对纺织品禁用偶氮的检测提供指导。

关键词： CPU-GPU heterogeneous parallel technique   Distinct Lattice Spring Model   Excavation of foundation   Modified Cam Clay   Parameter sensitivity   Soil-structure interaction  

摘要： The control of foundation deformation has garnered significant attention. This study focuses on understanding the deformation induced by excavation activities in real foundation construction scenarios. To accurately model the complex geomechanical responses, an enhanced Distinct Lattice Spring Model (DLSM) was developed. The Modified Cam Clay (MCC) model is employed to represent the nonlinear behaviour of the soil. Integration with one-dimensional structure elements is implemented to model support structures and their interactions with the soil. The birth–death particle method is utilized to simulate the excavation process of the foundation. To improve computational efficiency, a CPU-GPU heterogeneous parallel technique is employed. The enhanced DLSM produces consistent results with the finite element method when calculating foundation-bearing capacity and demonstrates relatively close results compared to finite difference methods when analyzing the stability of foundation slopes under different parameters. Finally, a three-dimensional numerical model is established using the proposed DLSM to simulate the deformation of the foundation caused by the excavations. The entire simulation task is divided into twelve stages, involving in-situ stress, a diaphragm wall, ten supporting structures, and ten excavations. A comparative analysis between the MCC model and the ZP (Zienkiewicz-Pande) model is conducted. The findings indicate that the calculation results of the two are consistent in the early stages of excavation, while those calculated by the MCC in the later stages are relatively small. Sensitivity analysis of the MCC parameters using orthogonal analysis reveals that the porosity of the soil has the greatest impact on the deformation of the foundation pit, followed by the slope of the swelling line, while the slope of the critical state line has a minimal impact. This work provides an alternative high-performance tool for engineering-scale deformation analysis of ge

关键词： 数码印花工厂   数字化管理   升级方案   节能减排  

摘要： 对数码印花工厂现状调研,探讨数字化管理的必要性和可行性,软件系统和硬件设备是数字化管理的核心,以此为基础提出相应的升级方案,为数码印花工厂的数字化管理提供参考和指导。

关键词： 微胶囊技术   制备方法   纺织品   应用  

摘要： 综述近年来微胶囊技术的研究进展及其在纺织领域的应用,根据微胶囊的制备原理不同,从化学法、物理法和物理化学法3个方面分别对微胶囊的制备方法进行介绍,如化学法主要包括界面聚合法、原位聚合法及乳液聚合法等,物理法主要包括喷雾干燥法、空气悬浮法、溶剂蒸发法等,物理化学法主要包括水相分离法和油相分离法。详细介绍了微胶囊在印花、染色、一般性整理、功能性整理和智能纺织品中的应用,并简述了微胶囊技术在纺织领域应用中未来发展趋势。

关键词： 乳腺癌   表皮生长因子受体   GATA结合蛋白3(GATA-3)   上皮性钙黏附蛋白   预后  

摘要： 目的探讨表皮生长因子受体(EGFR)、GATA结合蛋白3(GATA-3)、上皮性钙黏附蛋白(E-cad)在乳腺癌组织内的表达及其与患者预后的关系。方法选取89例乳腺癌患者,术中采集所有患者的癌组织与癌旁正常组织(距离病灶边缘≥3 cm),将其分别纳入观察组、对照组,统计对比2组EGFR、GATA-3、E-Cad阳性表达差异。另随访1年,统计对比不同EGFR、GATA-3、E-Cad表达患者的生存率。结果观察组EGFR、GATA-3阳性表达率高于对照组,E-Cad阳性表达率低于对照组,差异有统计学意义(P<0.05);EGFR、GATA-3、E-Cad表达与患者肿瘤的分化程度、淋巴结转移、临床分期有关,差异有统计学意义(P<0.05)。EGFR、GATA-3阳性表达患者的生存率低于阴性表达患者,E-Cad阴性表达患者的生存率低于阳性表达患者,差异有统计学意义(P<0.05)。结论EGFR、GATA-3在乳腺癌组织内呈高表达,E-Cad呈低表达,三者表达与乳腺癌患者的生存率具有紧密联系。

关键词： 大思政”工作格局   课程思政   实践课程体系  

摘要： 课程思政是“立德树人”教育根本任务的实施理念。在“大思政”工作格局下,课程改革要遵循因材施教,时代发展,注重改革的成效,本文通过《电气CAD技术》实践课程体系研究,将学生思想政治教育与实践教学深度结合,相比于传统的课堂教育,更注重培养学生严精细实的工匠精神以及解决实际问题的能力。在《电气CAD技术》实践课程体系实行过程中,深入挖掘课程相关思政元素,推行项目化的教学方法,持续修订完善课程实践标准,改革实践课程考核方法,《电气CAD技术》实践课程体系建设和教学已取得一定实效。

关键词： Hepatitis B virus   Capsid assembly modulators   Apoptosis   ANXA1   Annexin A1   Lipocortin I  

摘要： Chronic HBV infection is the leading cause of liver disease and of hepatocellular carcinoma. The improvement of antiviral therapy remains an unmet medical need. Capsid assembly modulators (CAMs) target the HBV core antigen (HBc) and inhibit HBV replication. Although CAM-A compounds are well-known inducers of aberrant viral capsid aggregates, their mechanisms of action in HBV-hepatocyte interactions are poorly understood. Recently, we demonstrated that CAM-A molecules lead to a sustained reduction of HBsAg in the serum of HBV replicating mice and induce HBc aggregation in the nucleus of HBc-expressing cells leading to cell death.